G620-0437 Screening compound: 2,4-difluoro-N~1~-{4-[6-(4-methylpiperazino)-3-pyridazinyl]phenyl}-1-benzenesulfonamide

G620-0437 Screening compound: 2,4-difluoro-N~1~-{4-[6-(4-methylpiperazino)-3-pyridazinyl]phenyl}-1-benzenesulfonamide
G620-0437 Screening compound: 2,4-difluoro-N~1~-{4-[6-(4-methylpiperazino)-3-pyridazinyl]phenyl}-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G620-0437
2,4-difluoro-N~1~-{4-[6-(4-methylpiperazino)-3-pyridazinyl]phenyl}-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G620-0437

Molecular Formula

C21H21F2N5O2S (C21 H21 F2 N5 O2 S)

Compound Name

2,4-difluoro-N~1~-{4-[6-(4-methylpiperazino)-3-pyridazinyl]phenyl}-1-benzenesulfonamide

IUPAC name

n/a

SMILES

CN(CC1)CCN1c(cc1)nnc1-c(cc1)ccc1NS(c(ccc(F)c1)c1F)(=O)=O

InChI

InChI=1S/C21H21F2N5O2S/c1-27-10-12-28(13-11-27)21-9-7-19(24-25-21)15-2-5-17(6-3-15)26-31(29,30)20-8-4-16(22)14-18(20)23/h2-9,14,26H,10-13H2,1H3

InChI Key

XIHPAOLTXZRKPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08010275

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.256

Distribution Coefficient, logD

2.683

Water Solubility, LogSw

-3.63

Polar Surface Area

68.752

Acid Dissociation Constant (pKa)

8.67

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G620-0437 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G620-0437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G620-0437?
Check Price and Availability of G620-0437, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G620-0437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G620-0437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G620-0437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G620-0437 available by request