G622-0616 Screening compound: 1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide

G622-0616 Screening compound: 1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide
G622-0616 Screening compound: 1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G622-0616
1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G622-0616

Molecular Formula

C19H16FN3O2 (C19 H16 FN3 O2)

Compound Name

1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

1-[(4-fluorophenyl)methyl]-2-oxo-N-(prop-2-en-1-yl)-12-dihydro-18-naphthyridine-3-carboxamide

SMILES

C=CCNC(C1=Cc2cccnc2N(Cc(cc2)ccc2F)C1=O)=O

InChI

InChI=1S/C19H16FN3O2/c1-2-9-22-18(24)16-11-14-4-3-10-21-17(14)23(19(16)25)12-13-5-7-15(20)8-6-13/h2-8,10-11H,1,9,12H2,(H,22,24)

InChI Key

VNCRCELRIDVUTL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08032811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

337.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.240

Distribution Coefficient, logD

2.240

Water Solubility, LogSw

-2.64

Polar Surface Area

50.198

Acid Dissociation Constant (pKa)

11.90

Base Dissociation Constant (pKb)

-0.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

G622-0616 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G622-0616 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G622-0616?
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What is the minimum amount of G622-0616 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G622-0616
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G622-0616
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G622-0616 available by request