G622-1289 Screening compound: 1-[(4-chlorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

G622-1289 Screening compound: 1-[(4-chlorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide
G622-1289 Screening compound: 1-[(4-chlorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G622-1289
1-[(4-chlorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G622-1289

Molecular Formula

C24H20ClN3O4 (C24 H20 ClN3 O4)

Compound Name

1-[(4-chlorophenyl)methyl]-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

IUPAC name

1-[(4-chlorophenyl)methyl]-N-(25-dimethoxyphenyl)-2-oxo-12-dihydro-18-naphthyridine-3-carboxamide

SMILES

COc(cc1)cc(NC(C2=Cc3cccnc3N(Cc(cc3)ccc3Cl)C2=O)=O)c1OC

InChI

InChI=1S/C24H20ClN3O4/c1-31-18-9-10-21(32-2)20(13-18)27-23(29)19-12-16-4-3-11-26-22(16)28(24(19)30)14-15-5-7-17(25)8-6-15/h3-13H,14H2,1-2H3,(H,27,29)

InChI Key

IQWMAIIFAWCLKT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08033380

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.89

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.288

Distribution Coefficient, logD

4.238

Water Solubility, LogSw

-4.66

Polar Surface Area

63.240

Acid Dissociation Constant (pKa)

8.31

Base Dissociation Constant (pKb)

-1.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

G622-1289 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G622-1289 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G622-1289?
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What is the minimum amount of G622-1289 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G622-1289
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G622-1289
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G622-1289 available by request