G634-0749 Screening compound: 2-(6-bromo-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide

G634-0749 Screening compound: 2-(6-bromo-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide
G634-0749 Screening compound: 2-(6-bromo-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G634-0749
2-(6-bromo-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G634-0749

Molecular Formula

C23H26BrN3O2 (C23 H26 BrN3 O2)

Compound Name

2-(6-bromo-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide

IUPAC name

2-(6-bromo-2-oxo-1234-tetrahydroquinolin-1-yl)-N-{4-[(piperidin-1-yl)methyl]phenyl}acetamide

SMILES

O=C(CN(C(CC1)=O)c(cc2)c1cc2Br)Nc1ccc(CN2CCCCC2)cc1

InChI

InChI=1S/C23H26BrN3O2/c24-19-7-10-21-18(14-19)6-11-23(29)27(21)16-22(28)25-20-8-4-17(5-9-20)15-26-12-2-1-3-13-26/h4-5,7-10,14H,1-3,6,11-13,15-16H2,(H,25,28)

InChI Key

AIQDRZRWPSPKKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15024005

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.360

Distribution Coefficient, logD

2.778

Water Solubility, LogSw

-4.13

Polar Surface Area

42.501

Acid Dissociation Constant (pKa)

11.93

Base Dissociation Constant (pKb)

8.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G634-0749 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with G634-0749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G634-0749?
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What is the minimum amount of G634-0749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G634-0749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G634-0749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G634-0749 available by request