G637-1005 Screening compound: N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

G637-1005 Screening compound: N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide
G637-1005 Screening compound: N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G637-1005
N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G637-1005

Molecular Formula

C25H33FN4O4S (C25 H33 FN4 O4 S)

Compound Name

N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

IUPAC name

N-[(1-ethylpyrrolidin-2-yl)methyl]-1-({5-[(1E)-2-(2-fluorophenyl)ethenyl]-3-methyl-12-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

SMILES

CCN1C(CNC(C(CC2)CCN2S(c2c(/C=C/c(cccc3)c3F)onc2C)(=O)=O)=O)CCC1

InChI

InChI=1S/C25H33FN4O4S/c1-3-29-14-6-8-21(29)17-27-25(31)20-12-15-30(16-13-20)35(32,33)24-18(2)28-34-23(24)11-10-19-7-4-5-9-22(19)26/h4-5,7,9-11,20-21H,3,6,8,12-17H2,1-2H3,(H,27,31)/t21-/m1/s1

InChI Key

ZLZGJQHPXNZUMZ-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD15024397

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

504.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.613

Distribution Coefficient, logD

1.349

Water Solubility, LogSw

-2.93

Polar Surface Area

81.785

Acid Dissociation Constant (pKa)

13.09

Base Dissociation Constant (pKb)

8.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.00

G637-1005 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with G637-1005 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G637-1005?
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What is the minimum amount of G637-1005 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G637-1005
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G637-1005
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G637-1005 available by request