G637-1358 Screening compound: 1-(2,5-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine

G637-1358 Screening compound: 1-(2,5-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine
G637-1358 Screening compound: 1-(2,5-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G637-1358
1-(2,5-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G637-1358

Molecular Formula

C33H42N4O4S (C33 H42 N4 O4 S)

Compound Name

1-(2,5-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine

IUPAC name

1-(25-dimethylphenyl)-4-[1-({3-methyl-5-[(1E)-2-(246-trimethylphenyl)ethenyl]-12-oxazol-4-yl}sulfonyl)piperidine-4-carbonyl]piperazine

SMILES

Cc1noc(/C=C/c2c(C)cc(C)cc2C)c1S(N(CC1)CCC1C(N(CC1)CCN1c1c(C)ccc(C)c1)=O)(=O)=O

InChI

InChI=1S/C33H42N4O4S/c1-22-7-8-24(3)30(21-22)35-15-17-36(18-16-35)33(38)28-11-13-37(14-12-28)42(39,40)32-27(6)34-41-31(32)10-9-29-25(4)19-23(2)20-26(29)5/h7-10,19-21,28H,11-18H2,1-6H3

InChI Key

DXOWCXANHXHQKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15024557

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

590.79

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

6.182

Distribution Coefficient, logD

6.182

Water Solubility, LogSw

-5.41

Polar Surface Area

73.073

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

5.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

G637-1358 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G637-1358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G637-1358?
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What is the minimum amount of G637-1358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G637-1358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G637-1358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G637-1358 available by request