G637-1380 Screening compound: N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

G637-1380 Screening compound: N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide
G637-1380 Screening compound: N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G637-1380
N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G637-1380

Molecular Formula

C28H32ClN3O4S (C28 H32 ClN3 O4 S)

Compound Name

N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(2,4,6-trimethylphenyl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

IUPAC name

N-(2-chloro-4-methylphenyl)-1-({3-methyl-5-[(1E)-2-(246-trimethylphenyl)ethenyl]-12-oxazol-4-yl}sulfonyl)piperidine-4-carboxamide

SMILES

Cc1noc(/C=C/c2c(C)cc(C)cc2C)c1S(N(CC1)CCC1C(Nc(ccc(C)c1)c1Cl)=O)(=O)=O

InChI

InChI=1S/C28H32ClN3O4S/c1-17-6-8-25(24(29)16-17)30-28(33)22-10-12-32(13-11-22)37(34,35)27-21(5)31-36-26(27)9-7-23-19(3)14-18(2)15-20(23)4/h6-9,14-16,22H,10-13H2,1-5H3,(H,30,33)

InChI Key

HUMRVWZKMKQVFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15024572

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

542.1

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.809

Distribution Coefficient, logD

5.808

Water Solubility, LogSw

-5.96

Polar Surface Area

75.858

Acid Dissociation Constant (pKa)

10.07

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

G637-1380 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G637-1380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G637-1380?
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What is the minimum amount of G637-1380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G637-1380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G637-1380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G637-1380 available by request