G639-1228 Screening compound: ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate

G639-1228 Screening compound: ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate
G639-1228 Screening compound: ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1228
ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1228

Molecular Formula

C24H25N5O4 (C24 H25 N5 O4)

Compound Name

ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate

IUPAC name

ethyl 3-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-amido}benzoate

SMILES

CCOC(c1cc(NC(C(CC2)CCN2C(c2n[nH]c(-c3ccncc3)c2)=O)=O)ccc1)=O

InChI

InChI=1S/C24H25N5O4/c1-2-33-24(32)18-4-3-5-19(14-18)26-22(30)17-8-12-29(13-9-17)23(31)21-15-20(27-28-21)16-6-10-25-11-7-16/h3-7,10-11,14-15,17H,2,8-9,12-13H2,1H3,(H,26,30)(H,27,28)

InChI Key

DTDLDMUDALICLD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147462

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.791

Distribution Coefficient, logD

2.790

Water Solubility, LogSw

-2.99

Polar Surface Area

92.650

Acid Dissociation Constant (pKa)

11.50

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

G639-1228 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G639-1228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1228?
Check Price and Availability of G639-1228, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1228 available by request