G639-1239 Screening compound: 1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

G639-1239 Screening compound: 1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole
G639-1239 Screening compound: 1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1239
1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1239

Molecular Formula

C23H23N5O2 (C23 H23 N5 O2)

Compound Name

1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-2,3-dihydro-1H-indole

IUPAC name

1-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}-23-dihydro-1H-indole

SMILES

O=C(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)N(CC1)c2c1cccc2

InChI

InChI=1S/C23H23N5O2/c29-22(28-14-9-17-3-1-2-4-21(17)28)18-7-12-27(13-8-18)23(30)20-15-19(25-26-20)16-5-10-24-11-6-16/h1-6,10-11,15,18H,7-9,12-14H2,(H,25,26)

InChI Key

BUBLLRPPQYMEJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147469

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.397

Distribution Coefficient, logD

2.395

Water Solubility, LogSw

-2.56

Polar Surface Area

64.484

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

G639-1239 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with G639-1239 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1239?
Check Price and Availability of G639-1239, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1239 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1239
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1239
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1239 available by request