G639-1243 Screening compound: 1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

G639-1243 Screening compound: 1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine
G639-1243 Screening compound: 1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1243
1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1243

Molecular Formula

C26H30N6O3 (C26 H30 N6 O3)

Compound Name

1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

IUPAC name

1-(2-methoxyphenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

SMILES

COc(cccc1)c1N(CC1)CCN1C(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)=O

InChI

InChI=1S/C26H30N6O3/c1-35-24-5-3-2-4-23(24)30-14-16-32(17-15-30)25(33)20-8-12-31(13-9-20)26(34)22-18-21(28-29-22)19-6-10-27-11-7-19/h2-7,10-11,18,20H,8-9,12-17H2,1H3,(H,28,29)

InChI Key

PHEZHBZHTPXBJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147471

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.247

Distribution Coefficient, logD

2.246

Water Solubility, LogSw

-2.55

Polar Surface Area

76.043

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G639-1243 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1243?
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What is the minimum amount of G639-1243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1243 available by request