G639-1292 Screening compound: 1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

G639-1292 Screening compound: 1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide
G639-1292 Screening compound: 1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1292
1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1292

Molecular Formula

C24H27N5O2 (C24 H27 N5 O2)

Compound Name

1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(2,4,6-trimethylphenyl)piperidine-4-carboxamide

IUPAC name

1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]-N-(246-trimethylphenyl)piperidine-4-carboxamide

SMILES

Cc(cc1C)cc(C)c1NC(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)=O

InChI

InChI=1S/C24H27N5O2/c1-15-12-16(2)22(17(3)13-15)26-23(30)19-6-10-29(11-7-19)24(31)21-14-20(27-28-21)18-4-8-25-9-5-18/h4-5,8-9,12-14,19H,6-7,10-11H2,1-3H3,(H,26,30)(H,27,28)

InChI Key

QMENRFVJKOIJII-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147492

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.713

Distribution Coefficient, logD

2.712

Water Solubility, LogSw

-2.52

Polar Surface Area

70.500

Acid Dissociation Constant (pKa)

11.48

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G639-1292 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1292 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1292?
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What is the minimum amount of G639-1292 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1292
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1292
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1292 available by request