G639-1317 Screening compound: N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

G639-1317 Screening compound: N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide
G639-1317 Screening compound: N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1317
N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1317

Molecular Formula

C22H22FN5O2 (C22 H22 FN5 O2)

Compound Name

N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)NCc(cc1)ccc1F

InChI

InChI=1S/C22H22FN5O2/c23-18-3-1-15(2-4-18)14-25-21(29)17-7-11-28(12-8-17)22(30)20-13-19(26-27-20)16-5-9-24-10-6-16/h1-6,9-10,13,17H,7-8,11-12,14H2,(H,25,29)(H,26,27)

InChI Key

MAQBNTMWEZSNAT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147502

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.727

Distribution Coefficient, logD

1.726

Water Solubility, LogSw

-1.63

Polar Surface Area

73.218

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G639-1317 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PLpro Library (6343 compounds)

Protein-Protein Interaction Library (218420 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Others
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1317 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1317?
Check Price and Availability of G639-1317, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1317 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1317
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1317
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1317 available by request