G639-1327 Screening compound: 1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

G639-1327 Screening compound: 1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine
G639-1327 Screening compound: 1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1327
1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1327

Molecular Formula

C25H27FN6O2 (C25 H27 FN6 O2)

Compound Name

1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

IUPAC name

1-(4-fluorophenyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazine

SMILES

O=C(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C25H27FN6O2/c26-20-1-3-21(4-2-20)30-13-15-32(16-14-30)24(33)19-7-11-31(12-8-19)25(34)23-17-22(28-29-23)18-5-9-27-10-6-18/h1-6,9-10,17,19H,7-8,11-16H2,(H,28,29)

InChI Key

PWFLYUJICYMVDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147507

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.397

Distribution Coefficient, logD

2.396

Water Solubility, LogSw

-2.47

Polar Surface Area

68.713

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

G639-1327 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with G639-1327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1327?
Check Price and Availability of G639-1327, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1327 available by request