G639-1345 Screening compound: 2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine

G639-1345 Screening compound: 2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine
G639-1345 Screening compound: 2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1345
2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1345

Molecular Formula

C23H26N8O2 (C23 H26 N8 O2)

Compound Name

2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine

IUPAC name

2-(4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carbonyl}piperazin-1-yl)pyrimidine

SMILES

O=C(C(CC1)CCN1C(c1n[nH]c(-c2ccncc2)c1)=O)N(CC1)CCN1c1ncccn1

InChI

InChI=1S/C23H26N8O2/c32-21(30-12-14-31(15-13-30)23-25-6-1-7-26-23)18-4-10-29(11-5-18)22(33)20-16-19(27-28-20)17-2-8-24-9-3-17/h1-3,6-9,16,18H,4-5,10-15H2,(H,27,28)

InChI Key

AXROJZHQEMXONO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147514

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.411

Distribution Coefficient, logD

1.410

Water Solubility, LogSw

-1.44

Polar Surface Area

87.076

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

G639-1345 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1345?
Check Price and Availability of G639-1345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1345 available by request