G639-1718 Screening compound: N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide

G639-1718 Screening compound: N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide
G639-1718 Screening compound: N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1718
N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1718

Molecular Formula

C24H27N5O2 (C24 H27 N5 O2)

Compound Name

N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide

IUPAC name

N-(2-phenylpropyl)-1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide

SMILES

CC(CNC(C(CCC1)CN1C(c1n[nH]c(-c2ccncc2)c1)=O)=O)c1ccccc1

InChI

InChI=1S/C24H27N5O2/c1-17(18-6-3-2-4-7-18)15-26-23(30)20-8-5-13-29(16-20)24(31)22-14-21(27-28-22)19-9-11-25-12-10-19/h2-4,6-7,9-12,14,17,20H,5,8,13,15-16H2,1H3,(H,26,30)(H,27,28)

InChI Key

IFBVQFBRDNBQPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147594

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.053

Distribution Coefficient, logD

3.052

Water Solubility, LogSw

-3.15

Polar Surface Area

73.152

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

33.30

G639-1718 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1718 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1718?
Check Price and Availability of G639-1718, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1718 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1718
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1718
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1718 available by request