G639-1735 Screening compound: 1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine

G639-1735 Screening compound: 1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine
G639-1735 Screening compound: 1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1735
1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1735

Molecular Formula

C24H26N6O4 (C24 H26 N6 O4)

Compound Name

1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine

IUPAC name

1-(furan-2-carbonyl)-4-{1-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}piperazine

SMILES

O=C(C(CCC1)CN1C(c1n[nH]c(-c2ccncc2)c1)=O)N(CC1)CCN1C(c1ccco1)=O

InChI

InChI=1S/C24H26N6O4/c31-22(28-10-12-29(13-11-28)24(33)21-4-2-14-34-21)18-3-1-9-30(16-18)23(32)20-15-19(26-27-20)17-5-7-25-8-6-17/h2,4-8,14-15,18H,1,3,9-13,16H2,(H,26,27)/t18-/m0/s1

InChI Key

MEGVZKIMPUUVPS-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27147602

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.855

Distribution Coefficient, logD

0.854

Water Solubility, LogSw

-1.20

Polar Surface Area

90.421

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

G639-1735 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-1735 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1735?
Check Price and Availability of G639-1735, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-1735 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1735
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1735
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1735 available by request