G639-1989 Screening compound: N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

G639-1989 Screening compound: N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide
G639-1989 Screening compound: N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-1989
N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-1989

Molecular Formula

C22H23N5O3 (C22 H23 N5 O3)

Compound Name

N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

IUPAC name

N-(4-methoxyphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-4-carboxamide

SMILES

COc(cc1)ccc1NC(C(CC1)CCN1C(c1n[nH]c(-c2cnccc2)c1)=O)=O

InChI

InChI=1S/C22H23N5O3/c1-30-18-6-4-17(5-7-18)24-21(28)15-8-11-27(12-9-15)22(29)20-13-19(25-26-20)16-3-2-10-23-14-16/h2-7,10,13-15H,8-9,11-12H2,1H3,(H,24,28)(H,25,26)

InChI Key

DOJAOKGWSSURNW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.870

Distribution Coefficient, logD

1.870

Water Solubility, LogSw

-1.87

Polar Surface Area

79.529

Acid Dissociation Constant (pKa)

11.62

Base Dissociation Constant (pKb)

3.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G639-1989 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G639-1989 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-1989?
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What is the minimum amount of G639-1989 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-1989
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-1989
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-1989 available by request