G639-2512 Screening compound: N-(3-fluoro-4-methylphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide
Chemical Structure Depiction of ChemDiv screening compound G639-2512
N-(3-fluoro-4-methylphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
G639-2512
Molecular Formula
C22H22FN5O2 (C22 H22 FN5 O2)
Compound Name
N-(3-fluoro-4-methylphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide
IUPAC name
N-(3-fluoro-4-methylphenyl)-1-[5-(pyridin-3-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carboxamide
SMILES
Cc(ccc(NC(C(CCC1)CN1C(c1n[nH]c(-c2cnccc2)c1)=O)=O)c1)c1F
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
407.45
Hydrogen Bond Acceptors Count
6.00
Hydrogen Bond Donors Count
2.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
7
Partition Coefficient, logP
2.628
Distribution Coefficient, logD
2.627
Water Solubility, LogSw
-2.65
Polar Surface Area
71.919
Acid Dissociation Constant (pKa)
10.00
Base Dissociation Constant (pKb)
3.73
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
27.30
G639-2512 in Drug Discovery
Included in Screening Libraries
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
Nonpeptide Peptidomimetics PPI Library (18997 compounds)
Protein Arginine Methyltransferases Library (27925 compounds)
Protein-Protein Interaction Library (218420 compounds)
Included in 1.7M Stock Database
- PPI modulators
- Epigenetic
- PPI modulators
- Mimetics
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Hemic and lymphatic
- Metabolic
- Others
References: we are preparing a list of scientific research reports with G639-2512 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)