G639-3129 Screening compound: 1-{1-[5-(PYRIDIN-2-YL)-1H-PYRAZOLE-3-CARBONYL]PIPERIDINE-3-CARBONYL}-2,3-DIHYDRO-1H-INDOLE

G639-3129 Screening compound: 1-{1-[5-(PYRIDIN-2-YL)-1H-PYRAZOLE-3-CARBONYL]PIPERIDINE-3-CARBONYL}-2,3-DIHYDRO-1H-INDOLE
G639-3129 Screening compound: 1-{1-[5-(PYRIDIN-2-YL)-1H-PYRAZOLE-3-CARBONYL]PIPERIDINE-3-CARBONYL}-2,3-DIHYDRO-1H-INDOLE alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-3129
1-{1-[5-(PYRIDIN-2-YL)-1H-PYRAZOLE-3-CARBONYL]PIPERIDINE-3-CARBONYL}-2,3-DIHYDRO-1H-INDOLE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-3129

Molecular Formula

C23H23N5O2 (C23 H23 N5 O2)

Compound Name

1-{1-[5-(PYRIDIN-2-YL)-1H-PYRAZOLE-3-CARBONYL]PIPERIDINE-3-CARBONYL}-2,3-DIHYDRO-1H-INDOLE

IUPAC name

1-{1-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperidine-3-carbonyl}-23-dihydro-1H-indole

SMILES

O=C(C(CCC1)CN1C(c1n[nH]c(-c2ncccc2)c1)=O)N(CC1)c2c1cccc2

InChI

InChI=1S/C23H23N5O2/c29-22(28-13-10-16-6-1-2-9-21(16)28)17-7-5-12-27(15-17)23(30)20-14-19(25-26-20)18-8-3-4-11-24-18/h1-4,6,8-9,11,14,17H,5,7,10,12-13,15H2,(H,25,26)/t17-/m0/s1

InChI Key

DJQIFBMLEKEIGO-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27147851

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.608

Distribution Coefficient, logD

2.608

Water Solubility, LogSw

-2.99

Polar Surface Area

64.037

Acid Dissociation Constant (pKa)

11.15

Base Dissociation Constant (pKb)

3.35

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

G639-3129 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G639-3129 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-3129?
Check Price and Availability of G639-3129, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G639-3129 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-3129
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-3129
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-3129 available by request