G639-3477 Screening compound: 1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine

G639-3477 Screening compound: 1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine
G639-3477 Screening compound: 1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-3477
1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-3477

Molecular Formula

C20H18FN5O2 (C20 H18 FN5 O2)

Compound Name

1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine

IUPAC name

1-(4-fluorobenzoyl)-4-[5-(pyridin-4-yl)-1H-pyrazole-3-carbonyl]piperazine

SMILES

O=C(c1n[nH]c(-c2ccncc2)c1)N(CC1)CCN1C(c(cc1)ccc1F)=O

InChI

InChI=1S/C20H18FN5O2/c21-16-3-1-15(2-4-16)19(27)25-9-11-26(12-10-25)20(28)18-13-17(23-24-18)14-5-7-22-8-6-14/h1-8,13H,9-12H2,(H,23,24)

InChI Key

NTPNQLRMGIWDRE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27147941

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.514

Distribution Coefficient, logD

1.513

Water Solubility, LogSw

-1.59

Polar Surface Area

65.261

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G639-3477 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G639-3477 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-3477?
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What is the minimum amount of G639-3477 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-3477
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-3477
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-3477 available by request