G639-3770 Screening compound: 1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine

G639-3770 Screening compound: 1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine
G639-3770 Screening compound: 1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G639-3770
1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G639-3770

Molecular Formula

C19H19N5O2S (C19 H19 N5 O2 S)

Compound Name

1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine

IUPAC name

1-(3-methylthiophene-2-carbonyl)-4-[5-(pyridin-2-yl)-1H-pyrazole-3-carbonyl]piperazine

SMILES

Cc1c(C(N(CC2)CCN2C(c2n[nH]c(-c3ncccc3)c2)=O)=O)scc1

InChI

InChI=1S/C19H19N5O2S/c1-13-5-11-27-17(13)19(26)24-9-7-23(8-10-24)18(25)16-12-15(21-22-16)14-4-2-3-6-20-14/h2-6,11-12H,7-10H2,1H3,(H,21,22)

InChI Key

ZFWXVIBVFLAHRI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27148072

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.163

Distribution Coefficient, logD

2.163

Water Solubility, LogSw

-2.58

Polar Surface Area

65.899

Acid Dissociation Constant (pKa)

11.15

Base Dissociation Constant (pKb)

3.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G639-3770 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G639-3770 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G639-3770?
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What is the minimum amount of G639-3770 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G639-3770
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G639-3770
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G639-3770 available by request