G642-2746 Screening compound: 2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]-6-methoxyphenyl acetate

G642-2746 Screening compound: 2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]-6-methoxyphenyl acetate
G642-2746 Screening compound: 2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]-6-methoxyphenyl acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound G642-2746
2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]-6-methoxyphenyl acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G642-2746

Molecular Formula

C25H23N3O5 (C25 H23 N3 O5)

Compound Name

2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl]-6-methoxyphenyl acetate

IUPAC name

2-[3-acetyl-5-(2-cyclopropylquinolin-4-yl)-23-dihydro-134-oxadiazol-2-yl]-6-methoxyphenyl acetate

SMILES

CC(N1N=C(c2cc(C3CC3)nc3ccccc23)OC1c1cccc(OC)c1OC(C)=O)=O

InChI

InChI=1S/C25H23N3O5/c1-14(29)28-25(18-8-6-10-22(31-3)23(18)32-15(2)30)33-24(27-28)19-13-21(16-11-12-16)26-20-9-5-4-7-17(19)20/h4-10,13,16,25H,11-12H2,1-3H3/t25-/m0/s1

InChI Key

APZYUGPRSNOHIX-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27148571

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.101

Distribution Coefficient, logD

2.252

Water Solubility, LogSw

-4.48

Polar Surface Area

72.388

Acid Dissociation Constant (pKa)

22.67

Base Dissociation Constant (pKb)

9.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.00

G642-2746 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G642-2746 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G642-2746?
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What is the minimum amount of G642-2746 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G642-2746
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G642-2746
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G642-2746 available by request