G644-0184 Screening compound: 1-{6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine

G644-0184 Screening compound: 1-{6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine
G644-0184 Screening compound: 1-{6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G644-0184
1-{6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G644-0184

Molecular Formula

C19H21F3N6 (C19 H21 F3 N6)

Compound Name

1-{6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine

IUPAC name

1-{6-ethyl-5-methyl-[124]triazolo[15-a]pyrimidin-7-yl}-4-[3-(trifluoromethyl)phenyl]piperazine

SMILES

CCc(c(C)nc1ncnn11)c1N(CC1)CCN1c1cccc(C(F)(F)F)c1

InChI

InChI=1S/C19H21F3N6/c1-3-16-13(2)25-18-23-12-24-28(18)17(16)27-9-7-26(8-10-27)15-6-4-5-14(11-15)19(20,21)22/h4-6,11-12H,3,7-10H2,1-2H3

InChI Key

KEEQHPVXJOMFEK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27148667

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.042

Distribution Coefficient, logD

3.915

Water Solubility, LogSw

-4.13

Polar Surface Area

37.835

Acid Dissociation Constant (pKa)

20.74

Base Dissociation Constant (pKb)

6.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

G644-0184 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with G644-0184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G644-0184?
Check Price and Availability of G644-0184, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G644-0184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G644-0184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G644-0184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G644-0184 available by request