G646-0424 Screening compound: ethyl 4-{2-[6,7-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamido}benzoate

G646-0424 Screening compound: ethyl 4-{2-[6,7-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamido}benzoate
G646-0424 Screening compound: ethyl 4-{2-[6,7-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G646-0424
ethyl 4-{2-[6,7-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G646-0424

Molecular Formula

C28H25N3O5 (C28 H25 N3 O5)

Compound Name

ethyl 4-{2-[6,7-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamido}benzoate

IUPAC name

ethyl 4-{2-[67-dimethyl-4-oxo-3-(pyridine-4-carbonyl)-14-dihydroquinolin-1-yl]acetamido}benzoate

SMILES

CCOC(c(cc1)ccc1NC(CN(C=C1C(c2ccncc2)=O)c(cc(C)c(C)c2)c2C1=O)=O)=O

InChI

InChI=1S/C28H25N3O5/c1-4-36-28(35)20-5-7-21(8-6-20)30-25(32)16-31-15-23(26(33)19-9-11-29-12-10-19)27(34)22-13-17(2)18(3)14-24(22)31/h5-15H,4,16H2,1-3H3,(H,30,32)

InChI Key

ISYFKHVWVPRNMN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27148984

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.52

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.258

Distribution Coefficient, logD

4.258

Water Solubility, LogSw

-4.14

Polar Surface Area

82.361

Acid Dissociation Constant (pKa)

11.03

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.90

G646-0424 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Endocrine
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G646-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G646-0424?
Check Price and Availability of G646-0424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G646-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G646-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G646-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G646-0424 available by request