G646-0463 Screening compound: 2-[6,7-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide

G646-0463 Screening compound: 2-[6,7-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide
G646-0463 Screening compound: 2-[6,7-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G646-0463
2-[6,7-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G646-0463

Molecular Formula

C27H25N3O5 (C27 H25 N3 O5)

Compound Name

2-[6,7-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide

IUPAC name

2-[67-dimethoxy-4-oxo-3-(pyridine-4-carbonyl)-14-dihydroquinolin-1-yl]-N-(2-ethylphenyl)acetamide

SMILES

CCc(cccc1)c1NC(CN(C=C1C(c2ccncc2)=O)c(cc(c(OC)c2)OC)c2C1=O)=O

InChI

InChI=1S/C27H25N3O5/c1-4-17-7-5-6-8-21(17)29-25(31)16-30-15-20(26(32)18-9-11-28-12-10-18)27(33)19-13-23(34-2)24(35-3)14-22(19)30/h5-15H,4,16H2,1-3H3,(H,29,31)

InChI Key

BHLXPPCGBXWVNY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27149006

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.016

Distribution Coefficient, logD

3.016

Water Solubility, LogSw

-3.32

Polar Surface Area

76.170

Acid Dissociation Constant (pKa)

12.92

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G646-0463 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G646-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G646-0463?
Check Price and Availability of G646-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G646-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G646-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G646-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G646-0463 available by request