G646-0509 Screening compound: N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamide

G646-0509 Screening compound: N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamide
G646-0509 Screening compound: N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G646-0509
N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G646-0509

Molecular Formula

C25H21N3O4 (C25 H21 N3 O4)

Compound Name

N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-1,4-dihydroquinolin-1-yl]acetamide

IUPAC name

N-benzyl-2-[7-methoxy-4-oxo-3-(pyridine-4-carbonyl)-14-dihydroquinolin-1-yl]acetamide

SMILES

COc(cc1)cc(N(CC(NCc2ccccc2)=O)C=C2C(c3ccncc3)=O)c1C2=O

InChI

InChI=1S/C25H21N3O4/c1-32-19-7-8-20-22(13-19)28(16-23(29)27-14-17-5-3-2-4-6-17)15-21(25(20)31)24(30)18-9-11-26-12-10-18/h2-13,15H,14,16H2,1H3,(H,27,29)

InChI Key

ZGVIGDTURPTJHK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27149038

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.657

Distribution Coefficient, logD

2.657

Water Solubility, LogSw

-3.23

Polar Surface Area

70.473

Acid Dissociation Constant (pKa)

13.20

Base Dissociation Constant (pKb)

0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

G646-0509 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G646-0509 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G646-0509?
Check Price and Availability of G646-0509, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G646-0509 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G646-0509
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G646-0509
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G646-0509 available by request