G652-2249 Screening compound: N-(2,5-diethoxyphenyl)-2-(furan-2-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

G652-2249 Screening compound: N-(2,5-diethoxyphenyl)-2-(furan-2-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
G652-2249 Screening compound: N-(2,5-diethoxyphenyl)-2-(furan-2-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G652-2249
N-(2,5-diethoxyphenyl)-2-(furan-2-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G652-2249

Molecular Formula

C21H23N5O3 (C21 H23 N5 O3)

Compound Name

N-(2,5-diethoxyphenyl)-2-(furan-2-yl)-5,6-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

IUPAC name

N-(25-diethoxyphenyl)-2-(furan-2-yl)-56-dimethyl-[124]triazolo[15-a]pyrimidin-7-amine

SMILES

CCOc(cc1)cc(Nc2c(C)c(C)nc3nc(-c4ccco4)nn23)c1OCC

InChI

InChI=1S/C21H23N5O3/c1-5-27-15-9-10-17(28-6-2)16(12-15)23-20-13(3)14(4)22-21-24-19(25-26(20)21)18-8-7-11-29-18/h7-12,23H,5-6H2,1-4H3

InChI Key

NIBRMLQHVWIBBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27149658

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.217

Distribution Coefficient, logD

4.211

Water Solubility, LogSw

-4.22

Polar Surface Area

61.903

Acid Dissociation Constant (pKa)

14.61

Base Dissociation Constant (pKb)

5.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

G652-2249 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G652-2249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G652-2249?
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What is the minimum amount of G652-2249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G652-2249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G652-2249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G652-2249 available by request