G652-5474 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

G652-5474 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
G652-5474 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G652-5474
N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G652-5474

Molecular Formula

C19H18ClN5O2 (C19 H18 ClN5 O2)

Compound Name

N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

IUPAC name

N-(3-chloro-4-methoxyphenyl)-2-(furan-2-yl)-5-propyl-[124]triazolo[15-a]pyrimidin-7-amine

SMILES

CCCc1nc2nc(-c3ccco3)nn2c(Nc(cc2)cc(Cl)c2OC)c1

InChI

InChI=1S/C19H18ClN5O2/c1-3-5-12-11-17(21-13-7-8-15(26-2)14(20)10-13)25-19(22-12)23-18(24-25)16-6-4-9-27-16/h4,6-11,21H,3,5H2,1-2H3

InChI Key

PKQJCTTYMQVHQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27149700

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.855

Distribution Coefficient, logD

4.848

Water Solubility, LogSw

-5.00

Polar Surface Area

56.738

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

G652-5474 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G652-5474 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G652-5474?
Check Price and Availability of G652-5474, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G652-5474 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G652-5474
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G652-5474
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G652-5474 available by request