G657-0345 Screening compound: 4-ethyl-N~3~-(4-methylphenyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

G657-0345 Screening compound: 4-ethyl-N~3~-(4-methylphenyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide
G657-0345 Screening compound: 4-ethyl-N~3~-(4-methylphenyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G657-0345
4-ethyl-N~3~-(4-methylphenyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G657-0345

Molecular Formula

C19H21N5O2 (C19 H21 N5 O2)

Compound Name

4-ethyl-N~3~-(4-methylphenyl)-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

IUPAC name

2-ethyl-N-(4-methylphenyl)-8-oxo-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-triene-4-carboxamide

SMILES

CCN(c(n1nc2)c2C(Nc2ccc(C)cc2)=O)C(CCNC2)=C2C1=O

InChI

InChI=1S/C19H21N5O2/c1-3-23-16-8-9-20-10-14(16)19(26)24-18(23)15(11-21-24)17(25)22-13-6-4-12(2)5-7-13/h4-7,11,20H,3,8-10H2,1-2H3,(H,22,25)

InChI Key

HZIOACUWHCKRDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27150057

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

351.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.895

Distribution Coefficient, logD

1.552

Water Solubility, LogSw

-2.60

Polar Surface Area

63.651

Acid Dissociation Constant (pKa)

11.02

Base Dissociation Constant (pKb)

7.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

G657-0345 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G657-0345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G657-0345?
Check Price and Availability of G657-0345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G657-0345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G657-0345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G657-0345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G657-0345 available by request