G666-0189 Screening compound: 1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

G666-0189 Screening compound: 1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea
G666-0189 Screening compound: 1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G666-0189
1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G666-0189

Molecular Formula

C21H23ClN4O3 (C21 H23 ClN4 O3)

Compound Name

1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

IUPAC name

1-(2-chloro-4-methylphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

SMILES

Cc(cc1)cc(Cl)c1NC(Nc1ncc(-c(cc2)ccc2OC)n1CCOC)=O

InChI

InChI=1S/C21H23ClN4O3/c1-14-4-9-18(17(22)12-14)24-21(27)25-20-23-13-19(26(20)10-11-28-2)15-5-7-16(29-3)8-6-15/h4-9,12-13H,10-11H2,1-3H3,(H2,23,24,25,27)

InChI Key

DJQNIZLZERGSRJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15027460

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.983

Distribution Coefficient, logD

4.968

Water Solubility, LogSw

-5.15

Polar Surface Area

59.830

Acid Dissociation Constant (pKa)

11.68

Base Dissociation Constant (pKb)

5.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G666-0189 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G666-0189 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G666-0189?
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What is the minimum amount of G666-0189 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G666-0189
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G666-0189
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G666-0189 available by request