G666-0199 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

G666-0199 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea
G666-0199 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G666-0199
1-(5-chloro-2,4-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G666-0199

Molecular Formula

C22H25ClN4O5 (C22 H25 ClN4 O5)

Compound Name

1-(5-chloro-2,4-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

IUPAC name

1-(5-chloro-24-dimethoxyphenyl)-3-[1-(2-methoxyethyl)-5-(4-methoxyphenyl)-1H-imidazol-2-yl]urea

SMILES

COCCn1c(NC(Nc(c(OC)c2)cc(Cl)c2OC)=O)ncc1-c(cc1)ccc1OC

InChI

InChI=1S/C22H25ClN4O5/c1-29-10-9-27-18(14-5-7-15(30-2)8-6-14)13-24-21(27)26-22(28)25-17-11-16(23)19(31-3)12-20(17)32-4/h5-8,11-13H,9-10H2,1-4H3,(H2,24,25,26,28)

InChI Key

FMJDPZUYMPQBIC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15027461

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.558

Distribution Coefficient, logD

4.542

Water Solubility, LogSw

-4.71

Polar Surface Area

75.091

Acid Dissociation Constant (pKa)

10.03

Base Dissociation Constant (pKb)

5.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G666-0199 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G666-0199 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G666-0199?
Check Price and Availability of G666-0199, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G666-0199 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G666-0199
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G666-0199
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G666-0199 available by request