G666-0419 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea

G666-0419 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea
G666-0419 Screening compound: 1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G666-0419
1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G666-0419

Molecular Formula

C21H23FN4O3 (C21 H23 FN4 O3)

Compound Name

1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea

IUPAC name

1-[(4-fluorophenyl)methyl]-3-[1-(2-methoxyethyl)-5-(3-methoxyphenyl)-1H-imidazol-2-yl]urea

SMILES

COCCn1c(NC(NCc(cc2)ccc2F)=O)ncc1-c1cc(OC)ccc1

InChI

InChI=1S/C21H23FN4O3/c1-28-11-10-26-19(16-4-3-5-18(12-16)29-2)14-23-20(26)25-21(27)24-13-15-6-8-17(22)9-7-15/h3-9,12,14H,10-11,13H2,1-2H3,(H2,23,24,25,27)

InChI Key

NPNTUZCLHCAITD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15027489

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.460

Distribution Coefficient, logD

3.381

Water Solubility, LogSw

-3.62

Polar Surface Area

61.850

Acid Dissociation Constant (pKa)

13.75

Base Dissociation Constant (pKb)

6.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G666-0419 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G666-0419 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G666-0419?
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What is the minimum amount of G666-0419 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G666-0419
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G666-0419
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G666-0419 available by request