G673-0146 Screening compound: 5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-N,N-dimethyl-6-oxo-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline-3-carboxamide

G673-0146 Screening compound: 5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-N,N-dimethyl-6-oxo-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline-3-carboxamide
G673-0146 Screening compound: 5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-N,N-dimethyl-6-oxo-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G673-0146
5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-N,N-dimethyl-6-oxo-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G673-0146

Molecular Formula

C24H27ClN4O4 (C24 H27 ClN4 O4)

Compound Name

5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-N,N-dimethyl-6-oxo-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxaline-3-carboxamide

IUPAC name

5-{[(5-chloro-2-methoxyphenyl)carbamoyl]methyl}-NN-dimethyl-6-oxo-5H6H6aH7H8H9H10H-pyrido[12-a]quinoxaline-3-carboxamide

SMILES

CN(C)C(c(cc1)cc(N2CC(Nc(cc(cc3)Cl)c3OC)=O)c1N(CCCC1)C1C2=O)=O

InChI

InChI=1S/C24H27ClN4O4/c1-27(2)23(31)15-7-9-18-20(12-15)29(24(32)19-6-4-5-11-28(18)19)14-22(30)26-17-13-16(25)8-10-21(17)33-3/h7-10,12-13,19H,4-6,11,14H2,1-3H3,(H,26,30)/t19-/m1/s1

InChI Key

IPQXVDBUPZURHI-LJQANCHMSA-N

MDL Number (MFCD)

MFCD27150433

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.827

Distribution Coefficient, logD

1.820

Water Solubility, LogSw

-2.97

Polar Surface Area

63.874

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

1.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

G673-0146 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G673-0146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G673-0146?
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What is the minimum amount of G673-0146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G673-0146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G673-0146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G673-0146 available by request