G674-0271 Screening compound: N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide

G674-0271 Screening compound: N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide
G674-0271 Screening compound: N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G674-0271
N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G674-0271

Molecular Formula

C25H30N6O3 (C25 H30 N6 O3)

Compound Name

N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide

IUPAC name

N-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-4-methyl-2-(4-methylphenyl)-35-dioxo-2345-tetrahydro-124-triazine-6-carboxamide

SMILES

CCN1CCN(Cc(cc2)ccc2NC(C(C(N2C)=O)=NN(c3ccc(C)cc3)C2=O)=O)CC1

InChI

InChI=1S/C25H30N6O3/c1-4-29-13-15-30(16-14-29)17-19-7-9-20(10-8-19)26-23(32)22-24(33)28(3)25(34)31(27-22)21-11-5-18(2)6-12-21/h5-12H,4,13-17H2,1-3H3,(H,26,32)

InChI Key

JUVOWYIYUXWIPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15028468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.559

Distribution Coefficient, logD

1.627

Water Solubility, LogSw

-2.90

Polar Surface Area

72.643

Acid Dissociation Constant (pKa)

7.56

Base Dissociation Constant (pKb)

8.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

G674-0271 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with G674-0271 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G674-0271?
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What is the minimum amount of G674-0271 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G674-0271
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G674-0271
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G674-0271 available by request