G675-1845 Screening compound: N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-1,3,4-thiadiazole-2,5-dicarboxamide

G675-1845 Screening compound: N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-1,3,4-thiadiazole-2,5-dicarboxamide
G675-1845 Screening compound: N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-1,3,4-thiadiazole-2,5-dicarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G675-1845
N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-1,3,4-thiadiazole-2,5-dicarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G675-1845

Molecular Formula

C20H21N5O2S (C20 H21 N5 O2 S)

Compound Name

N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-1,3,4-thiadiazole-2,5-dicarboxamide

IUPAC name

N2-{3-[methyl(phenyl)amino]propyl}-N5-phenyl-134-thiadiazole-25-dicarboxamide

SMILES

CN(CCCNC(c1nnc(C(Nc2ccccc2)=O)s1)=O)c1ccccc1

InChI

InChI=1S/C20H21N5O2S/c1-25(16-11-6-3-7-12-16)14-8-13-21-17(26)19-23-24-20(28-19)18(27)22-15-9-4-2-5-10-15/h2-7,9-12H,8,13-14H2,1H3,(H,21,26)(H,22,27)

InChI Key

HRLAVKSRAHUOKS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15028885

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.338

Distribution Coefficient, logD

2.333

Water Solubility, LogSw

-2.91

Polar Surface Area

74.293

Acid Dissociation Constant (pKa)

10.17

Base Dissociation Constant (pKb)

8.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G675-1845 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G675-1845 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G675-1845?
Check Price and Availability of G675-1845, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G675-1845 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G675-1845
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G675-1845
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G675-1845 available by request