G677-0046 Screening compound: N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide

G677-0046 Screening compound: N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
G677-0046 Screening compound: N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G677-0046
N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G677-0046

Molecular Formula

C20H16ClN3OS (C20 H16 ClN3 OS)

Compound Name

N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-3-methyl-6-phenylimidazo[21-b][13]thiazole-2-carboxamide

SMILES

Cc1c(C(NCc(cc2)ccc2Cl)=O)sc2nc(-c3ccccc3)cn12

InChI

InChI=1S/C20H16ClN3OS/c1-13-18(19(25)22-11-14-7-9-16(21)10-8-14)26-20-23-17(12-24(13)20)15-5-3-2-4-6-15/h2-10,12H,11H2,1H3,(H,22,25)

InChI Key

AMUIAPMXLDXEJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08318735

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.89

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.721

Distribution Coefficient, logD

4.721

Water Solubility, LogSw

-4.91

Polar Surface Area

33.855

Acid Dissociation Constant (pKa)

11.78

Base Dissociation Constant (pKb)

4.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G677-0046 in Drug Discovery

Included in Screening Libraries

Human GPCR Annotated Library (5539 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with G677-0046 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G677-0046?
Check Price and Availability of G677-0046, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G677-0046 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G677-0046
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G677-0046
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G677-0046 available by request