G702-8378 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[3,2-b]quinazolin-9-amine

G702-8378 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[3,2-b]quinazolin-9-amine
G702-8378 Screening compound: N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[3,2-b]quinazolin-9-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G702-8378
N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[3,2-b]quinazolin-9-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G702-8378

Molecular Formula

C23H21ClFN5 (C23 H21 ClFN5)

Compound Name

N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H,6H,7H,8H-[1,2,4]triazolo[3,2-b]quinazolin-9-amine

IUPAC name

N-(3-chloro-4-fluorophenyl)-2-[(4-methylphenyl)methyl]-5H6H7H8H-[124]triazolo[32-b]quinazolin-9-amine

SMILES

Cc1ccc(Cc2nn3c(Nc(cc4)cc(Cl)c4F)c(CCCC4)c4nc3n2)cc1

InChI

InChI=1S/C23H21ClFN5/c1-14-6-8-15(9-7-14)12-21-28-23-27-20-5-3-2-4-17(20)22(30(23)29-21)26-16-10-11-19(25)18(24)13-16/h6-11,13,26H,2-5,12H2,1H3

InChI Key

OGZOCMKBABSYLN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27152246

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.9

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.891

Distribution Coefficient, logD

5.887

Water Solubility, LogSw

-6.07

Polar Surface Area

42.884

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

2.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

G702-8378 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antifungal Library (16415 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G702-8378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G702-8378?
Check Price and Availability of G702-8378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G702-8378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G702-8378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G702-8378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G702-8378 available by request