G714-0181 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea

G714-0181 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea
G714-0181 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G714-0181
3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G714-0181

Molecular Formula

C25H25N3O2 (C25 H25 N3 O2)

Compound Name

3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea

IUPAC name

3-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-1-(4-ethylphenyl)urea

SMILES

CCc(cc1)ccc1NC(NCc(cc1)cc(CC2)c1N2C(c1ccccc1)=O)=O

InChI

InChI=1S/C25H25N3O2/c1-2-18-8-11-22(12-9-18)27-25(30)26-17-19-10-13-23-21(16-19)14-15-28(23)24(29)20-6-4-3-5-7-20/h3-13,16H,2,14-15,17H2,1H3,(H2,26,27,30)

InChI Key

IEYJBHKEILHSEU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27153374

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.705

Distribution Coefficient, logD

4.705

Water Solubility, LogSw

-4.21

Polar Surface Area

49.542

Acid Dissociation Constant (pKa)

13.93

Base Dissociation Constant (pKb)

0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G714-0181 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G714-0181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G714-0181?
Check Price and Availability of G714-0181, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G714-0181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G714-0181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G714-0181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G714-0181 available by request