G714-0205 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea

G714-0205 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea
G714-0205 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G714-0205
3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G714-0205

Molecular Formula

C23H20BrN3O2 (C23 H20 BrN3 O2)

Compound Name

3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea

IUPAC name

3-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-1-(3-bromophenyl)urea

SMILES

O=C(c1ccccc1)N(CC1)c2c1cc(CNC(Nc1cccc(Br)c1)=O)cc2

InChI

InChI=1S/C23H20BrN3O2/c24-19-7-4-8-20(14-19)26-23(29)25-15-16-9-10-21-18(13-16)11-12-27(21)22(28)17-5-2-1-3-6-17/h1-10,13-14H,11-12,15H2,(H2,25,26,29)

InChI Key

PZTHQSCCAYCCHQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27153389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.583

Distribution Coefficient, logD

4.583

Water Solubility, LogSw

-4.32

Polar Surface Area

49.542

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G714-0205 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with G714-0205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G714-0205?
Check Price and Availability of G714-0205, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G714-0205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G714-0205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G714-0205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G714-0205 available by request