G714-0242 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(2,4-difluorophenyl)urea

G714-0242 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(2,4-difluorophenyl)urea
G714-0242 Screening compound: 3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(2,4-difluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G714-0242
3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(2,4-difluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G714-0242

Molecular Formula

C23H19F2N3O2 (C23 H19 F2 N3 O2)

Compound Name

3-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(2,4-difluorophenyl)urea

IUPAC name

3-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-1-(24-difluorophenyl)urea

SMILES

O=C(c1ccccc1)N(CC1)c2c1cc(CNC(Nc(ccc(F)c1)c1F)=O)cc2

InChI

InChI=1S/C23H19F2N3O2/c24-18-7-8-20(19(25)13-18)27-23(30)26-14-15-6-9-21-17(12-15)10-11-28(21)22(29)16-4-2-1-3-5-16/h1-9,12-13H,10-11,14H2,(H2,26,27,30)

InChI Key

JFOZZQYZXSYMTE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15029904

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.692

Distribution Coefficient, logD

3.691

Water Solubility, LogSw

-4.03

Polar Surface Area

48.845

Acid Dissociation Constant (pKa)

10.37

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G714-0242 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G714-0242 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G714-0242?
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What is the minimum amount of G714-0242 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G714-0242
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G714-0242
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G714-0242 available by request