G715-1174 Screening compound: 3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea

G715-1174 Screening compound: 3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea
G715-1174 Screening compound: 3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G715-1174
3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G715-1174

Molecular Formula

C23H21ClN4O2 (C23 H21 ClN4 O2)

Compound Name

3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea

IUPAC name

3-(5-chloro-2-methoxyphenyl)-1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]urea

SMILES

COc(ccc(Cl)c1)c1NC(NCC(c1c[nH]c2c1cccc2)c1cnccc1)=O

InChI

InChI=1S/C23H21ClN4O2/c1-30-22-9-8-16(24)11-21(22)28-23(29)27-13-18(15-5-4-10-25-12-15)19-14-26-20-7-3-2-6-17(19)20/h2-12,14,18,26H,13H2,1H3,(H2,27,28,29)/t18-/m1/s1

InChI Key

OAGLSMZSWKESEF-GOSISDBHSA-N

MDL Number (MFCD)

MFCD27153426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.241

Distribution Coefficient, logD

4.236

Water Solubility, LogSw

-4.72

Polar Surface Area

59.913

Acid Dissociation Constant (pKa)

9.56

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

G715-1174 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G715-1174 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G715-1174?
Check Price and Availability of G715-1174, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G715-1174 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G715-1174
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G715-1174
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G715-1174 available by request