G715-1227 Screening compound: 1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea

G715-1227 Screening compound: 1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea
G715-1227 Screening compound: 1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G715-1227
1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G715-1227

Molecular Formula

C23H22N4OS (C23 H22 N4 OS)

Compound Name

1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea

IUPAC name

1-[2-(1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-3-[3-(methylsulfanyl)phenyl]urea

SMILES

CSc1cc(NC(NCC(c2c[nH]c3c2cccc3)c2cnccc2)=O)ccc1

InChI

InChI=1S/C23H22N4OS/c1-29-18-8-4-7-17(12-18)27-23(28)26-14-20(16-6-5-11-24-13-16)21-15-25-22-10-3-2-9-19(21)22/h2-13,15,20,25H,14H2,1H3,(H2,26,27,28)/t20-/m1/s1

InChI Key

UHJUJELCXGKXGN-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD15029913

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.448

Distribution Coefficient, logD

4.446

Water Solubility, LogSw

-4.20

Polar Surface Area

52.981

Acid Dissociation Constant (pKa)

12.70

Base Dissociation Constant (pKb)

4.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

13.00

G715-1227 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Cardiovascular Library (22201 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cardiovascular

References: we are preparing a list of scientific research reports with G715-1227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G715-1227?
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What is the minimum amount of G715-1227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G715-1227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G715-1227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G715-1227 available by request