G715-1380 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea

G715-1380 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea
G715-1380 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G715-1380
3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G715-1380

Molecular Formula

C26H24F3N3O3 (C26 H24 F3 N3 O3)

Compound Name

3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea

IUPAC name

3-[2-(34-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[3-(trifluoromethyl)phenyl]urea

SMILES

COc(ccc(C(CNC(Nc1cccc(C(F)(F)F)c1)=O)c1c[nH]c2c1cccc2)c1)c1OC

InChI

InChI=1S/C26H24F3N3O3/c1-34-23-11-10-16(12-24(23)35-2)20(21-15-30-22-9-4-3-8-19(21)22)14-31-25(33)32-18-7-5-6-17(13-18)26(27,28)29/h3-13,15,20,30H,14H2,1-2H3,(H2,31,32,33)/t20-/m1/s1

InChI Key

QDJGZVGQBGJFHL-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD15029959

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.856

Distribution Coefficient, logD

5.856

Water Solubility, LogSw

-6.06

Polar Surface Area

58.724

Acid Dissociation Constant (pKa)

10.48

Base Dissociation Constant (pKb)

-1.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

G715-1380 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G715-1380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G715-1380?
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What is the minimum amount of G715-1380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G715-1380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G715-1380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G715-1380 available by request