G715-1381 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea

G715-1381 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea
G715-1381 Screening compound: 3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G715-1381
3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G715-1381

Molecular Formula

C27H29N3O3 (C27 H29 N3 O3)

Compound Name

3-[2-(3,4-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea

IUPAC name

3-[2-(34-dimethoxyphenyl)-2-(1H-indol-3-yl)ethyl]-1-[(4-methylphenyl)methyl]urea

SMILES

Cc1ccc(CNC(NCC(c2c[nH]c3c2cccc3)c(cc2)cc(OC)c2OC)=O)cc1

InChI

InChI=1S/C27H29N3O3/c1-18-8-10-19(11-9-18)15-29-27(31)30-16-22(20-12-13-25(32-2)26(14-20)33-3)23-17-28-24-7-5-4-6-21(23)24/h4-14,17,22,28H,15-16H2,1-3H3,(H2,29,30,31)/t22-/m1/s1

InChI Key

UIPUWIQOUWJBET-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD15029960

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.485

Distribution Coefficient, logD

4.485

Water Solubility, LogSw

-4.41

Polar Surface Area

60.046

Acid Dissociation Constant (pKa)

13.38

Base Dissociation Constant (pKb)

-1.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

G715-1381 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G715-1381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G715-1381?
Check Price and Availability of G715-1381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G715-1381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G715-1381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G715-1381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G715-1381 available by request