G716-0827 Screening compound: N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-1,3,5-trimethyl-1H-pyrazole-4-sulfonamide

G716-0827 Screening compound: N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-1,3,5-trimethyl-1H-pyrazole-4-sulfonamide
G716-0827 Screening compound: N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-1,3,5-trimethyl-1H-pyrazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G716-0827
N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-1,3,5-trimethyl-1H-pyrazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G716-0827

Molecular Formula

C22H23FN4O2S (C22 H23 FN4 O2 S)

Compound Name

N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-1,3,5-trimethyl-1H-pyrazole-4-sulfonamide

IUPAC name

N-[2-(4-fluorophenyl)-2-(1H-indol-3-yl)ethyl]-135-trimethyl-1H-pyrazole-4-sulfonamide

SMILES

Cc(n(C)nc1C)c1S(NCC(c1c[nH]c2c1cccc2)c(cc1)ccc1F)(=O)=O

InChI

InChI=1S/C22H23FN4O2S/c1-14-22(15(2)27(3)26-14)30(28,29)25-13-19(16-8-10-17(23)11-9-16)20-12-24-21-7-5-4-6-18(20)21/h4-12,19,24-25H,13H2,1-3H3/t19-/m1/s1

InChI Key

ZMYUIOLBEUBLCU-LJQANCHMSA-N

MDL Number (MFCD)

MFCD15029999

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.986

Distribution Coefficient, logD

2.985

Water Solubility, LogSw

-3.35

Polar Surface Area

66.435

Acid Dissociation Constant (pKa)

10.07

Base Dissociation Constant (pKb)

-1.54

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.70

G716-0827 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Antibacterial Compounds Library (13827 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G716-0827 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G716-0827?
Check Price and Availability of G716-0827, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G716-0827 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G716-0827
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G716-0827
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G716-0827 available by request