G716-1617 Screening compound: 1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide

G716-1617 Screening compound: 1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide
G716-1617 Screening compound: 1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G716-1617
1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G716-1617

Molecular Formula

C21H21F2N5O2S (C21 H21 F2 N5 O2 S)

Compound Name

1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide

IUPAC name

1-(difluoromethyl)-5-methyl-N-[2-(1-methyl-1H-indol-3-yl)-2-(pyridin-3-yl)ethyl]-1H-pyrazole-4-sulfonamide

SMILES

Cc(n(C(F)F)nc1)c1S(NCC(c1cn(C)c2c1cccc2)c1cnccc1)(=O)=O

InChI

InChI=1S/C21H21F2N5O2S/c1-14-20(12-25-28(14)21(22)23)31(29,30)26-11-17(15-6-5-9-24-10-15)18-13-27(2)19-8-4-3-7-16(18)19/h3-10,12-13,17,21,26H,11H2,1-2H3/t17-/m1/s1

InChI Key

QPLHPUGTDAHVRK-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD15030016

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.212

Distribution Coefficient, logD

2.208

Water Solubility, LogSw

-2.41

Polar Surface Area

67.389

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

5.33

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

G716-1617 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cardiovascular
Agro:
  • Agro
  • Agro
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G716-1617 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G716-1617?
Check Price and Availability of G716-1617, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G716-1617 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G716-1617
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G716-1617
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G716-1617 available by request