G718-0727 Screening compound: N-{2-[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]ethyl}-2,5-dimethylbenzene-1-sulfonamide

G718-0727 Screening compound: N-{2-[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]ethyl}-2,5-dimethylbenzene-1-sulfonamide
G718-0727 Screening compound: N-{2-[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]ethyl}-2,5-dimethylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G718-0727
N-{2-[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]ethyl}-2,5-dimethylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G718-0727

Molecular Formula

C18H19ClN4O2S (C18 H19 ClN4 O2 S)

Compound Name

N-{2-[5-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]ethyl}-2,5-dimethylbenzene-1-sulfonamide

IUPAC name

N-{2-[5-(4-chlorophenyl)-1H-124-triazol-3-yl]ethyl}-25-dimethylbenzene-1-sulfonamide

SMILES

Cc1cc(S(NCCc2n[nH]c(-c(cc3)ccc3Cl)n2)(=O)=O)c(C)cc1

InChI

InChI=1S/C18H19ClN4O2S/c1-12-3-4-13(2)16(11-12)26(24,25)20-10-9-17-21-18(23-22-17)14-5-7-15(19)8-6-14/h3-8,11,20H,9-10H2,1-2H3,(H,21,22,23)

InChI Key

KSOZIPAKVOPDJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27153786

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.89

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.378

Distribution Coefficient, logD

4.365

Water Solubility, LogSw

-4.52

Polar Surface Area

76.614

Acid Dissociation Constant (pKa)

8.94

Base Dissociation Constant (pKb)

0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G718-0727 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G718-0727 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G718-0727?
Check Price and Availability of G718-0727, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G718-0727 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G718-0727
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G718-0727
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G718-0727 available by request