G718-0908 Screening compound: N-(2-{5-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-3-yl}ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

G718-0908 Screening compound: N-(2-{5-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-3-yl}ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide
G718-0908 Screening compound: N-(2-{5-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-3-yl}ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G718-0908
N-(2-{5-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-3-yl}ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G718-0908

Molecular Formula

C22H26N4O2S (C22 H26 N4 O2 S)

Compound Name

N-(2-{5-[(4-methylphenyl)methyl]-1H-1,2,4-triazol-3-yl}ethyl)-5,6,7,8-tetrahydronaphthalene-2-sulfonamide

IUPAC name

N-(2-{5-[(4-methylphenyl)methyl]-1H-124-triazol-3-yl}ethyl)-5678-tetrahydronaphthalene-2-sulfonamide

SMILES

Cc1ccc(Cc2nc(CCNS(c3cc(CCCC4)c4cc3)(=O)=O)n[nH]2)cc1

InChI

InChI=1S/C22H26N4O2S/c1-16-6-8-17(9-7-16)14-22-24-21(25-26-22)12-13-23-29(27,28)20-11-10-18-4-2-3-5-19(18)15-20/h6-11,15,23H,2-5,12-14H2,1H3,(H,24,25,26)

InChI Key

PCTFCPMFXFPHIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27153855

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.816

Distribution Coefficient, logD

4.815

Water Solubility, LogSw

-4.60

Polar Surface Area

77.525

Acid Dissociation Constant (pKa)

9.89

Base Dissociation Constant (pKb)

2.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G718-0908 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G718-0908 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G718-0908?
Check Price and Availability of G718-0908, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G718-0908 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G718-0908
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G718-0908
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G718-0908 available by request