G721-0141 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[1,3-dimethyl-2,4-dioxo-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetamide

G721-0141 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[1,3-dimethyl-2,4-dioxo-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetamide
G721-0141 Screening compound: N-(3-chloro-4-methylphenyl)-2-{[1,3-dimethyl-2,4-dioxo-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G721-0141
N-(3-chloro-4-methylphenyl)-2-{[1,3-dimethyl-2,4-dioxo-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G721-0141

Molecular Formula

C21H23ClN4O3S (C21 H23 ClN4 O3 S)

Compound Name

N-(3-chloro-4-methylphenyl)-2-{[1,3-dimethyl-2,4-dioxo-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl]sulfanyl}acetamide

IUPAC name

N-(3-chloro-4-methylphenyl)-2-{[13-dimethyl-24-dioxo-6-(propan-2-yl)-1H2H3H4H-pyrido[23-d]pyrimidin-5-yl]sulfanyl}acetamide

SMILES

CC(C)c(c(SCC(Nc1cc(Cl)c(C)cc1)=O)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C21H23ClN4O3S/c1-11(2)14-9-23-19-17(20(28)26(5)21(29)25(19)4)18(14)30-10-16(27)24-13-7-6-12(3)15(22)8-13/h6-9,11H,10H2,1-5H3,(H,24,27)

InChI Key

YOFKGNCTHIFTES-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08326319

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.96

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.752

Distribution Coefficient, logD

4.751

Water Solubility, LogSw

-5.01

Polar Surface Area

64.640

Acid Dissociation Constant (pKa)

10.76

Base Dissociation Constant (pKb)

4.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G721-0141 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G721-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

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What is the minimum amount of G721-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G721-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G721-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G721-0141 available by request