G721-0148 Screening compound: 5-{[(3-chlorophenyl)methyl]sulfanyl}-1,3-dimethyl-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

G721-0148 Screening compound: 5-{[(3-chlorophenyl)methyl]sulfanyl}-1,3-dimethyl-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione
G721-0148 Screening compound: 5-{[(3-chlorophenyl)methyl]sulfanyl}-1,3-dimethyl-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound G721-0148
5-{[(3-chlorophenyl)methyl]sulfanyl}-1,3-dimethyl-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G721-0148

Molecular Formula

C19H20ClN3O2S (C19 H20 ClN3 O2 S)

Compound Name

5-{[(3-chlorophenyl)methyl]sulfanyl}-1,3-dimethyl-6-(propan-2-yl)-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

IUPAC name

5-{[(3-chlorophenyl)methyl]sulfanyl}-13-dimethyl-6-(propan-2-yl)-1H2H3H4H-pyrido[23-d]pyrimidine-24-dione

SMILES

CC(C)c(c(SCc1cccc(Cl)c1)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C19H20ClN3O2S/c1-11(2)14-9-21-17-15(18(24)23(4)19(25)22(17)3)16(14)26-10-12-6-5-7-13(20)8-12/h5-9,11H,10H2,1-4H3

InChI Key

GVEOPEVLMXUXLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08326327

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.91

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.620

Distribution Coefficient, logD

4.618

Water Solubility, LogSw

-4.82

Polar Surface Area

41.490

Acid Dissociation Constant (pKa)

21.22

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

G721-0148 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

CNS Targets (44014 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G721-0148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G721-0148?
Check Price and Availability of G721-0148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G721-0148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G721-0148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G721-0148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G721-0148 available by request